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S-015 / S-015-1ML updated item number format
Sirolimus (Rapamycin)
1.0 mg/mL in Acetonitrile | Certified Reference Material
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A Certified Spiking Solution® of an immunosuppressant and narrow therapeutic index drug used to prevent rejection in organ transplantation. This certified calibration material is suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays to ensure patients remain within the drug’s narrow therapeutic range. The Snap-N-Spike® format allows laboratories to eliminate weighing operations of hazardous substances such as sirolimus, significantly reducing occupational exposure hazards related to handling of acutely toxic powders, and provides the ability to spike into their matrix of choice just before use.
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Concentration:
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1.0 mg/mL
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Solvent:
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Acetonitrile
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Unit Size:
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1 mL/ampoule
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CAS Number:
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53123-88-9
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Chemical Formula:
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C51H79NO13
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Molecular Weight:
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914.17
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Certificate of Analysis:
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US List Price:
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UN Number, Class, PG 1648, 3, II
Safety Data Sheet
HS Code
3822.90.0000
▶ High Throughput Simultaneous Analysis of Immunosuppressants by ESI/ESI Dual Source Coaxial Flow Ion Source LC-MS/MS System | Frenny Ruparelia; Hui Qiao; Heather Gamble; Sha Joshua Ye, IONICS Mass Spectrometry Group inc., 2011
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▶ LC/MS/MS Analysis of Immunosuppressant Drugs in Human Plasma on Ascentis® Express F5 after SPE Using HybridSPE®-Phospholipid | Sigma-Aldrich®, 2015
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▶ LC/MS/MS Analysis of Immunosuppressant Drugs on apHera™ C18 | Sigma-Aldrich®, 2015
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▶ UHPLC Separation of Temsirolimus and Sirolimus on Titan™ C18 | Sigma-Aldrich®, 2015
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▶ Variables that Impact Immunosuppressant LC-MS/MS Analysis | Josh Cooper, Beth Marek, Isil Dilek, and Uma Sreenivasan, Cerilliant, 2010
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